Questions about Long-term use of Statin Drugs during Cardiovascular Problems Side Affects
We have talked about the medical treatment of coronary heart disease. If there are two legs and aspirin is one of them, then statin drug is the other.
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In the process of taking statins, friends with coronary heart disease will encounter various problems, such as:
1. Why should I take statins for coronary heart disease?
2. What is the target value of taking statin for coronary
heart disease?
3. What to check before and after taking statin?
4. What are the most common side effects of statins?
5. How to reduce the common side effects of statins?
6. What is the difference between rosuvast and atorvastatin?
7. When is the most appropriate time to take statins?
8. Other drugs and affected by fruits?
9. Are there any alternative drugs for statins?
10. Do you continue to take it after the blood lipid reaches
the standard?
Today we will interpret statins for everyone, and try our
best to know ourselves and enemies in the process of taking statins in the
future!
1. Why should I take statins, a lipid-lowering drug for coronary heart disease?
First of all, it is clear that statins are not only lipid-lowering drugs, statins can lower bad blood lipids such as cholesterol, low-density lipoprotein, triglycerides, and can also increase high-density lipoprotein, a good blood lipid.
Everyone knows that scurvy is the culprit of
coronary heart disease. Good blood lipids can prevent coronary heart disease,
so friends with coronary heart disease need to take statins.
What's more important is that statins not only regulate fat,
but also anti-inflammatory and stabilize plaque. What do you mean?
Aspirin prevents thrombosis. Only when plaque ruptures can
thrombus form. How can we reduce plaque rupture?
A statin is a drug that stabilizes plaque, prevents plaque
rupture, and can even reverse plaque. Therefore, as long as it is coronary
heart disease, regardless of high blood lipids, you need to take statins for a
long time.
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| Chart on Statin Side Effects |
2. What drugs are available for statins and what are the goals of taking statins?
Statins are not a drug, but a class of drugs. There are currently three generations (recommended dose):
- The first generation includes lovastatin (20mg), simvastatin (20mg), and pravastatin (10mg)
- The second generation includes fluvastatin (40mg)
- The third generation includes atorvastatin (20mg), rosuvastatin (10mg) and pitavastatin (2mg)
Coronary heart disease taking statins mainly depends on low-density lipoprotein, and the goal is to reach 1.8mmol/L.
If the low-density
still does not reach 1.8 when the dosage is increased, then we suggest that the
base low-density should be reduced by at least 50%.
3. What items need to be checked before and after taking statins?
Before taking:
Four blood lipids: cholesterol, low-density lipoprotein,
high-density lipoprotein, triglycerides.
Blood sugar, liver function, kidney function, creatine
kinase.
The above items must be reviewed 1-3 months after taking.
If there is no abnormality, recheck at least once a year in
the future.
4. What are common side effects of statins?
Common side
effects can vary between different statin categories, but common side effects are:
- Feeling Sick
- Headache
- Dizziness
- Fewer Blood Platelet Count
- Fatigue or
physical weakness
- Some digestive system troubles, such
as farting, constipation,
diarrhoea, indigestion
- Muscular pain
- Sleeping disorders
5. What are uncommon side effects of statins?
The uncommon
side effects of statins can possibly be:
- Hair Loss
- Memory Abnormality
- Becoming Sick
- Pinching pins and
needles
- Dermal conditions such as acne or an itchy red rash
- Liver inflammation (hepatitis) which may cause flu like
symptoms
- Pancreatic inflammation (pancreatitis), which can cause abdominal pain
- Sexual conditions, such as libido loss (lower sex drive) or ED (erectile
dysfunction)
What are some rare side effects of statins?
Rare side
effects of statins include:
- Weakness in muscles (myopathy)
- Sensational loss tingling
in nerve endings of feet and hands (peripheral
neuropathy)
- Tendon conditions (tough cords of tissue that connect muscles to bones are referable as tendons)
What are the side affects of statin on muscles?
Statins may occasionally cause muscle inflammation (swelling) including damage.
You may need to talk to your
doctor if you have muscle pain, tenderness or weakness that cannot be explained e.g. pain that is not attributable to any physical exertion.
The doctor may may need to conduct a blood test
to measure a substance in your blood referable as creatine kinase (CK), which is
released into blood when muscles are inflamed or damaged.
If the CK in your blood is more than 5 times the normal level, your doctor may advise to stop taking statin.
Regular physical exercises can sometimes lead to a rise in CK,
so you should ideally tell your doctor if you are exercising too much.
Once your
CK level has returned to normal, your doctor may suggest you start over with statin again, but with relatively lower doses.
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Author's Bio
Name: Gwynneth May
Educational Qualification: MBBS, MD (Medicine) Gold Medalist
Profession: Doctor
Experience: 16 Years of Work Experience as a Medical Practitioner
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